Board Thread:Speculation House/@comment-36285558-20190202212117/@comment-25110963-20190211064923

That's the curious thing. Salem is a mutated kind of human. She's not a creature of destruction like the Grimm, but basing on what Jinn said in her wording, she has the potential and craving for destruction like the Grimm. After her dip in the pools. Her immortality is what kept her from dying and instead it mutated her into what she is today. Humans by design were a creation of Light and Darkness and has potential to do good or bad. But the Eyes don't work on humans in general. That was stated so, but it hurt Cinder for obvious reasons.

So to answer your question, we don't know if the Silver Eyes could or could not work on her. It's a coin flip right now.