Board Thread:Off Topic/@comment-25353464-20141223015814/@comment-25555436-20150109022837

You just had to grab every ammo you found along the way until that level, along with any weapon you see that you think could be usefull. If you upgrade a weapon, it will always be useful. The shitty pistol you start with? Fully upgraded it, and it tears off limbs with 1-3 shots in Nightmare dificulty.

As for the twins...yes.